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Ready-to-use ADME assay kits with built in quality control.

TRANSIL Plasma Protein Binding Assays

Assessing plasma protein binding is important because only the unbound fraction (fu) of a drug can penetrate cell membranes. Thus, only a drug’s ...

The TRANSIL HSA Binding Kit estimates the binding of drugs to human serum albumin (HSA) and predicts the plasma pro...

The TRANSIL AGP Binding Kit estimates the binding of drugs to human α1 acid glycoprotein (AGP/AAG). The assay kit m...

The TRANSIL PPB Binding Kit estimates the binding of drugs to human serum albumin (HSA) and human alpha-1 glycoprot...

The TRANSIL RSA Binding Kit estimates the binding of drugs to rat serum albumin (RSA) and predicts the plasma prote...

The TRANSIL MSA Binding Kit estimates the binding of drugs to mouse serum albumin (MSA) and predicts the plasma pro...

Compounds binding strongly to plasma proteins frequently result in overly small compound concentrations that are di...

Drug transport can broadly be divided into transcellular and paracellular processes. Transcellular movement, which involves the passage of drugs ...

The TRANSIL Brain Absorption kit estimates the binding of drugs to brain tissue and predicts the disposition of dru...

The TRANSIL Intestinal Absorption kit measures the affinity of drugs to phosphatidylcholine membranes. It is not on...

When estimating intrinsic clearance in metabolic stability incubations with microsomes or hepatocytes, the disappea...

The TRANSIL MA kit assesses the affinity of compounds to phosphatidylcholine membranes. Movement through membranes ...

Assessing plasma protein binding is important because only the unbound fraction (fu) of a drug can penetrate cell membranes.